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Guangji Pharmaceutical Advances 1,000 t/a (1%) Vitamin B12 Comprehensive Utilisation Project

by Chris Han
April 29, 2025

Company Dynamics Update

In April 2025, Guangji Pharmaceutical (Mengzhou) Co., Ltd. (Guangji Pharmaceutical) announced the successful completion and acceptance of its 1,000 t/a (1%) vitamin B12 comprehensive utilisation project, marking a significant milestone in its expansion within the vitamin and pharmaceutical sectors.

Project Overview and Investment Details

The project represents a total investment of RMB 2,960.00 million (approximately USD 412.40 million), with RMB 51.00 million (USD 7.11 million) dedicated specifically to environmental protection initiatives. The project occupies a site area of 83,670 square meters and is designed to deliver:

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  • 480 t/a of vitamin B12 food additives (calculated at 1%)
  • 20 t/a of mixed food additives (0.1%-2% specifications)
  • 500 t/a of mixed feed additives (0.1%-2% specifications)
  • 4,000 t/a of by-product organic fertilizer

It is noteworthy that the originally approved 1 t/a adenosine cobalamin food additive line was not constructed and was excluded from the acceptance assessment.

Environmental Protection Measures

The scope of the project acceptance included comprehensive assessments of:

  • Exhaust gas treatment
  • Wastewater treatment
  • Noise pollution control
  • Solid waste management

The production processes and associated environmental facilities were found compliant with relevant regulatory standards, supporting Guangji Pharmaceutical’s commitment to sustainable operations.

Company Background

Guangji Pharmaceutical, based at No. 81 Huaihe Avenue, Mengzhou High-Tech Industrial Development Zone, Jiaozuo City, focuses on the research, development, production, and sales of active pharmaceutical ingredients (APIs), notably vitamin B2 and vitamin B12. The company currently operates a production line with a 3,000 t/a capacity for vitamin B2, reinforcing its strong presence in the vitamin sector.

Industry Implications

The successful acceptance of Guangji Pharmaceutical’s vitamin B12 project strengthens China’s competitive position in the global vitamin B12 supply chain. The project’s emphasis on environmental sustainability also highlights the industry’s growing focus on green manufacturing practices, aligning with national and international standards.


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